SPSS Inc announced on July 28, 2009 that it was being acquired by IBM for US$1.2 billion.[17] Because of a dispute about ownership of the name "SPSS", between 2009 and 2010, the product was referred to as PASW (Predictive Analytics SoftWare).[18] As of January 2010, it became "SPSS: An IBM Company". Complete transfer of business to IBM was done by October 1, 2010. By that date, SPSS: An IBM Company ceased to exist. IBM SPSS is now fully integrated into the IBM Corporation, and is one of the brands under IBM Software Group's Business Analytics Portfolio, together with IBM Algorithmics, IBM Cognos and IBM OpenPages.
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This product presents information from the Census of Population for various levels of geography, including provinces and territories, census metropolitan areas, communities and census tracts. Data are from the Census of Population and include characteristics for: population, age, sex, dwellings, families, marital status, language, income, education and labour as examples.
This product presents information from the Census of Population focusing on the Aboriginal identity population of various geographic areas. These geographic areas include: Canada, provinces and territories, census metropolitan areas and census agglomerations, census divisions, census subdivisions, Métis settlements, Inuit regions, Indian band and Tribal Council areas, modern treaty and self-government agreement areas and historic treaty areas. Data are available for the Aboriginal identity population by age groups for selected socio-demographic characteristics.
This interactive mapping application makes it easy to find many places in Canada, see them on a map, and get basic geographic and demographic data for those places. To find a specific place of interest, users can click and zoom in on a map of Canada or they can search by place name, postal code, street address, street intersection or geographic code. GeoSearch will display the appropriate map showing boundaries and other features. GeoSearch automatically shows, for the selected places, the types of geographic area and its relationship to other geographic areas. A thematic mapping option is also available for selected census topics (for selected levels of geography). GeoSearch includes links to census reference maps and various census products.
This product provides thematic maps associated with Human Activity and the Environment, 2021, covering various aspects of ecosystem accounts, including ecosystem extent and condition. The maps are based on the principles of ecosystem accounting and use multiple datasets from a variety of sources.
This product describes the similarities and differences between two sets of United Nations (UN) guidelines for greenhouse gas (GHG) emissions: the United Nations System of Environmental-Economic Accounts (SEEA) and the United Nations Framework Convention on Climate Change (UNFCCC). Statistics Canada's Greenhouse Gas Account is compiled based on the SEEA guidelines, while the National GHG Inventory is prepared by Environment and Climate Change Canada in accordance with the UNFCCC.
This product includes many safeguards to prevent the identification of any one person or household. The CTNS PUMF is for users who prefer to do their own analysis by focusing on specific sub-groups in the population or by cross-classifying variables.
The Public-Use Microdata File (PUMF) for the Survey of Household Spending (SHS) provides information on household expenditures as well as selected information on dwelling characteristics and household equipment. The production of this file includes many safeguards to prevent the identification of any one person or household.
The international trade monthly interactive dashboard is a comprehensive analytical tool that presents monthly changes in Canada's international merchandise trade data on a balance of payments basis. Four sections are available: 1) a page summarizing the monthly results; 2) a dashboard showing data by product; 3) a dashboard on Canada's principal trading partners; and 4) graphs that show change in price and volume indices on international trade.
MATLAB helps you take your ideas beyond the desktop. You can run your analyses on larger data sets and scale up to clusters and clouds. MATLAB code can be integrated with other languages, enabling you to deploy algorithms and applications within web, enterprise, and production systems.
Objective: To examine receptors for advanced glycation end-products Gly82Ser polymorphism in patients of type 2 diabetes with comorbid depression.Methods: The case-control study was conducted at Fujian Provincial Hospital, Fuzhou, China, between December 2011 and December 2012, and comprised unrelated Chinese Han patients of type 2 diabetes, and diabetics with diagnosed clinical depression. Gly82Ser polymorphism polymorphism was determined using polymerase chain reaction amplification-high resolution melting curve protocol. Serum levels of endogenous secretory receptor for advanced glycation end products were measured using enzyme-linked immunosorbent assay. SPSS 16 was used for data analysis. Results: Of the 114 subjects, 72(63.15%) were clinically depressed. Lower levels of endogenous secretory receptor were found in the depression group compared with the other group (p=0.049). No difference in genotypes or allele frequencies existed between the two groups (p>0.05). Gly82Ser carriers had significantly higher Hamilton Rating Scale scores (p
IntroductionExtensive epidemiological data indicates that diabetes greatly advances the risk of depression.1,2 Besides the psychological stress associated with chronic disease, it is now being questioned if there is a common biological mechanism between diabetes and depression. In recent years, Cytokine hypothesis is one of the research focuses in the pathogenesis of depression, which postulated that cytokines may cause depressive illness3 and depression is a psycho-neuro-immunological disorder. 4 A study clearly stated that depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression. 5 Besides, in patients with type 2 diabetes (T2D), the interaction between receptors for advanced glycation end products (RAGE) with its ligands results in the activation of multiple signalling pathways, which, in turn, increase the secretion of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α). These considerations led to the hypothesis that the increasing cytokines derived from activation of the interaction between RAGE with its ligands contributed to the pathology of diabetic depression. However, soluble RAGE (sRAGE) as an isoform of RAGE plays a protective role by neutralising the harmful effects due to its special structures that carry all the extracellular domains, but lack the transmembrane and cytoplasmic domains. A previous study6 showed that, compared with the common T2Ds, diabetics with comorbid depression had lower endogenous secretory RAGE (esRAGE) level and higher serum high-sensitivity C-reactive protein (hsCRP) level, confirming the association between T2D with comorbid depression and RAGE ligands. Recent studies have shown that advanced glycation end-product (AGE) inhibitors prevent or limit diabetes-accelerated medial calcification, thus inhibiting the association of AGE-RAGE or the downstream signalling-reduced medial calcification in diabetes. 7 RAGE-mediated regulation of adiposity and inflammation may attribute to T2D and diabetic vascular complications. 8 However, the mechanism is still unclear. Growing evidence 9-11indicates that circulating levels ofsRAGE are associated with RAGE Gly82Ser (G82S) polymorphism, and Ser82 allele carriers had lower plasma levels of sRAGE. RAGE G82S polymorphism. (Gly82Ser, rs2070600) is a non-synonymous single nucleotide polymorphism (SNP) which is identified within the V-type immunoglobulin (IG) domain in the extracellular region of the receptor, and leads to a change from glycine to serine at codon 82 in exon 3.9 Additionally, the Ser82 allele has been shown in in-vitro studies to increase ligand affinity in transfection cells, which, upon further analysis, demonstrated upregulation of key pro-inflammatory signal transduction pathways, and the prompted Ser82 alleles may play an important role in inflammatory disease.10 However, information regarding the relation between these polymorphisms and serum esRAGE in T2D patients with comorbid depression remains limited. The current study was planned to explore whether these polymorphisms and levels of serum esRAGE were related in T2D patients with depression as a comorbidity. 2ff7e9595c
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